The importance of aortic dissection and genetic testing


Taiwanese artist Huang Hongsheng (little ghost) died suddenly at home on September 16 at the age of 36. The agent Dino appeared for an interview and confirmed that the death was caused by vascular blockage caused by “aortic dissection”. Aortic dissection was like an untimely bomb with a family history, it is more common in patients with poorly controlled hypertension. It is common in autumn and winter. Other risks such as rare Marfan syndrome, congenital connective tissue abnormalities, double-valve aortic stenosis, etc., make the aorta dilate. Once the blood vessel expands to be unable to bear, it will burst and die suddenly. Usually, patients will not have any abnormal conditions, but when aortic dissection occurs, they may feel strong tearing pain, and the fatality rate can be said to be quite high. Therefore, early diagnosis helps to survive.

Lihpao Life Science provides a number of genetic cardiac risk tests, two of which are closely related to “aortic dissection”. The next-generation sequencing technology is used to detect the entire exon region of the relevant gene to screen whether the patient has related causes. Disease mutations can help physicians determine the diagnosis, evaluate the prognosis, give appropriate treatment, medication, and follow up properly.

Gene detection of thoracic aortic aneurysm dissection syndrome

Thoracic Aortic Aneurysm and Dissection (TAAD) is caused by tearing of the aortic intima and separation of the aortic wall (including the ascending aorta), which may cause bleeding, cardiac tamponade, or insufficient blood supply to the coronary arteries. Cause death. In acute aortic syndrome, the death rate caused by aortic rupture is as high as 50%, which often surprises people. For TAAD detected early before rupture or dissection, the risk of operative mortality is less than 15%. Early diagnosis helps survival. This testing service uses next-generation sequencing to detect the entire exon region of 34 TAAD-related genes to screen patients for related pathogenic mutations, which can help physicians determine diagnosis, assess prognosis, give appropriate treatment, medication and Track it properly.

Atherosclerosis gene detection

Atherosclerosis (ATS) is a complex chronic inflammatory disease that easily leads to a variety of cardiovascular diseases (CVD), including ischemic heart disease, cerebrovascular disease, carotid stenosis, aortic aneurysm and thickening of aortic dissection Wait. Many studies have shown that atherosclerosis is caused by the interaction between genes and the environment. Lihpao Life Science uses the next-generation sequencing gene detection platform to design the “Atherosclerosis (ATS) Genome Kit”, which detects gene mutations related to atherosclerosis, and evaluates the correlation between atherosclerosis and gene mutations in individual cases. In order to facilitate the follow-up medication and treatment reference.

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